The Agglutination of Autoclaved Hemolytic Strepto-

نویسنده

  • SUNG J. LIAO
چکیده

Thulin (1-3) has recently reported an agglutination test, using human serum and hemolytic streptococci which had been treated at a high temperature. He found that in human sera the agglutination titers were significantly higher in samples from patients with rheumatic fever and with rheumatoid arthritis than in others and that the titers observed in both diseases were similar. This test would seem to offer an unusually simple technique for the measurement of antibodies which occur in active streptococcal diseases and in rheumatoid arthritis. Many streptococcal agglutination tests have been described and proposed in the past, but the principle of subjecting the bacterial suspension to a temperature of 1200 C prior to its use as an agglutinogen (4), is a new suggestion insofar as its clinical application for the study of streptococcal diseases is concerned; for this reason alone it has seemed to deserve further investigation. It is the purpose of this paper therefore to report confirmation of Thulin's observation that sera from patients with rheumatic fever and rheumatoid arthritis agglutinate autoclaved streptococci and to present the results of further investigations utilizing this technique.

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تاریخ انتشار 2013